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What medications interact with Accutane? Some products that may interact with this drug are: tetracyclines (such as minocycline, tetracycline), vitamin A-type drugs (such as acitretin, bexarotene), vitamin A, drugs that cause bone loss (for example, anti-seizure drugs such as phenytoin, corticosteroids such as prednisone).
Does adapalene make acne worse? During the first 3 weeks you are using adapalene, your acne may seem to get worse before it gets better. You should not stop using adapalene if your acne seems worse at first, unless irritation or other symptoms become severe.
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