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What is the best drug for hypothyroidism? The most common treatment is levothyroxine (Levoxyl, Synthroid, Tirosint, Unithroid, Unithroid Direct), a man-made version of the thyroid hormone thyroxine (T4). It acts just like the hormone your thyroid gland normally makes. The right dose can make you feel a lot better.
How long does levothyroxine stay in your system? "T4 has a five to nine-day long half-life, which means that once you have become stable on it, it will take as many as nine days for 50% of the dose to clear the body.
