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What medications can cause osteonecrosis of the jaw? The following is a breakdown of number of cases linked to various medications from the total of 17,119 ONJ cases: Bisphosphonates: Zoledronate: 11,490 (67.1%) Alendronate : 7,307 (42.7%) RANKL inhibitor: Denosumab: 1,184 (6.9%) Antiangiogenic agents: Bevacizumab: 703 (4.1%) m-TOR inhibitors: Everolimus: 84 (0.5%)
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