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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment option for chronic weight reduction in addition to a reduced-calorie diet and physical exercise.

Using two separate drugs to lose weight can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight reduction and the people who go through it you ought to err assisting caution and permit the FDA do its job and demand some research be done so the public is aware of the side effects and hazards of the medications before we bring them. Keep in mind that drug companies will be in business to generate income and that they would say almost anything to keep people on his or her medications.

Researchers found out that participants using this drug for the year, lost weight within 4 weeks and have kept the extra weight off through the entire 56 weeks with the study. Contrave is often a combination with the drugs naltrexone and bupropion, which appears to reflect a brand new trend of weight-loss drugs that are made up of more than one active ingredient, which might make them far better and safer.

Combo-pilling is the newest fad or also the newest into the future under scrutiny and thus it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular is the fact that at the time of right now there aren't any long term prescription slimming capsules that have been approved by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be licensed by the FDA.

Seizures can be a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug may also raise blood pressure level and heartbeat, and must not be used in people who have a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with all the drug.

The FDA also warned that Contrave can raise hypertension and heartbeat and must not used in patients with uncontrolled high blood pressure, and also by you aren't heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. Patients using a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert medical researchers and patients towards the increased chance of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stop smoking.


Other people who should not use Contrave are patients being affected by bulimia, anorexia nervosa, anyone using opiods, and patients undergoing an 'abrupt discontinuation of alcohol, benzodiazepines, barbiturates and antiepileptic drugs.' Lastly Concave should not be prescribed for girls who are pregnant or trying to become pregnant.

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